APCTP-토토 분석 Joint Semina

토토 분석TEXT-JUSTIFY: inter-ideograph; TEXT-ALIGN: justify토토 분석=5style=FONT-WEIGHT: bold; FONT-토토 분석: 18pt; FONT-FAMILY: 맑은 고딕APCTP-POSTECH
Joint Seminastyle=FONT-토토 분석: 10pt; FONT-FAMILY: 맑은 고딕

style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움*Title :
style=FONT-WEIGHT: bold; FONT-토토 분석: 16pt; FONT-FAMILY: 돋움Cortical Plasticity
and the Cortical "Operating Regime"

style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움*Speaker : Klaus
Obermayer (Bernsteinw:st=onCenter for Computational Neuroscience and w:st=onBerlinw:st=onUniversity of
Technology)

style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움*Location : APCTP
style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움세미나실lang=EN-US (무은재 기념관lang=EN-US 512호lang=EN-US)

style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움*Date & Time :
2007.08.31(lang=EN-US금)
style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움오후lang=EN-US
3시style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움

style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움*Abstrack

style=FONT-토토 분석: 10pt; FONT-FAMILY: 돋움In my talk I will first discuss results
of developmental perturbations imposed on the visual system of adolescent cats
through retinal lesions (cf. [1]). Using a computational model of visual
cortical responses, I will show that the lesion induced changes of neuronal
response properties are inconsistent with the common assumption that the
underlying plasticity of intracortical connections is dependent on the temporal
correlation of pre- and post-synaptic action potentials
("Hebbian"correlation dependent plasticity). They
are, however, consistent with the hypothesis that this plasticity is dependent
upon the temporal order of pre- and post-synaptic action potentials ("causal"
spike timing-dependent plasticity). Spike timing-dependent plasticity - in
contrast to correlation dependent (Hebbian) changes - causes visual cortical
receptive fields to converge by creating a competition between neurons for the
control of spike timing within the network. The spatial scale of this
competition appears to depend on the balance of excitation and inhibition and
and can in principle be controlled by synaptic scaling type mechanisms. This
reveals a novel way by which the capacity of cortical learning rules to transfer
response properties between neurons can be effectively switched on and
off.

style=FONT-토토 분석: 10pt; FONT-FAMILY: 돋움But what is the cortical "operating
regime" to begin with? Using a computational model of a cortical network in
primary visual cortex we analysed how much evidence recent intracellular
measurements from cat primary visual cortex (cf. [2]) provide for a particular
cortical "operating point". Using a Bayesian analysis we find, that the
experimental data most strongly support a regime where the local cortical
network provides dominant excitatory and inhibitory recurrent inputs (compared
to the feedforward drive). Most interestingly, the data supports an operating
regime which is close to the border to instability. Hence it is conceivable,
that modulatory effects like visual attention may briefly shift the operating
point into these regimes, leading to an increased sensitivity of cortical
responses to visual inputs.

style=FONT-토토 분석: 10pt; FONT-FAMILY: 돋움The presentation is based in part
on:

style=FONT-토토 분석: 10pt; FONT-FAMILY: 돋움[1] Young J., Waleszczyk W., Wang C.,
Calford M., Dreher B. and Obermayer

style=FONT-토토 분석: 10pt; FONT-FAMILY: 돋움     K. (2007), Nat. Neurosci. 10,
887ff [2007].

style=FONT-토토 분석: 10pt; FONT-FAMILY: 돋움[2] Marino, Schummers, w:st=onLyon, Schwabe, Beck, Wiesing, Obermayer &
Sur,

style=FONT-토토 분석: 10pt; FONT-FAMILY: 돋움     Nature Neurosci. 8, 194ff
[2005].

style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움-style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움주 관lang=EN-US
: POSTCH NCSL Lab.

style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움-style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움후 원lang=EN-US
: 토토 분석,뇌연구센터lang=EN-US,토토 분석학과lang=EN-US

style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움*style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움문의lang=EN-US
: 토토 분석학과 김승환 교수lang=EN-US(☏lang=EN-US279-8671,href=mailto:swan@토토 분석.ac.krswan@토토 분석.ac.kr)

style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; FONT-FAMILY: 돋움뇌연구센터
장나영lang=EN-US (☏lang=EN-US279-2961,href=mailto:jny1321@토토 분석.ac.krjny1321@토토 분석.ac.krcolor=navy )color=navy 토토 분석=2style=FONT-WEIGHT: bold; FONT-토토 분석: 10pt; COLOR: navy