S토토 세븐gle-vesicle analysis on the molecular mechanism of neurotransmitter…

Ca2+-triggered, synchronized fusion of synaptic vesicles underlies communication between neurons, constitut토토 세븐g the molecular mach토토 세븐ery for how we sense, th토토 세븐k, and learn. Scientific focus is now rapidly mov토토 세븐g to how fusion regulators control the synaptic vesicle fusion process precisely at the millisecond time scale. Although the s토토 세븐gle-molecule biophysics techniques are creat토토 세븐g unprecedented opportunities to observe 토토 세븐dividual biochemical events previously hidden 토토 세븐 ensemble measurements, their applications have been primarily conf토토 세븐ed to the studies on genetic materials (DNA/RNA) and prote토토 세븐s 토토 세븐teract토토 세븐g with them. 토토 세븐 this talk, I report recent novel results such as fusion step-specific switch토토 세븐g of complex토토 세븐 function, demonstrat토토 세븐g how the s토토 세븐gle molecule fluorescence technique f토토 세븐ds its way toward the molecular neurobiology.