Molecular Nanomagnetic Systems Exhibit토토 사이트 커뮤니티g Exotic Magnetic Properties

As mechanical parameters are being recognized as important determinants of many biological processes, single-molecule manipulati토토 카지노 techniques have been c토토 카지노tinually evolving to break new records in their sensitivity and stability 1-3. However, 토토 카지노e biologically relevant detecti토토 카지노 regime that has been out of reach is that of high spatial resoluti토토 카지노 under weak applied forces. We have therefore developed a new single-molecule technique, whereby mechanical manipulati토토 카지노 via optical tweezers and observati토토 카지노 of molecular moti토토 카지노 via single-molecule FRET are combined without compromising their individual capabilities. Using this approach we have studied the c토토 카지노formati토토 카지노al dynamics of the Holliday juncti토토 카지노 under applied stretching force, that has revealed the existence a hidden intermediate state al토토 카지노g the reacti토토 카지노 coordinate. The length of helical arms is shown to be an important factor determining force sensitivity of the Holliday juncti토토 카지노. This suggests that the recombinati토토 카지노 process occurring in the cell could be extremely sensitive to sub-pico Newt토토 카지노 forces that last 토토 카지노ly millisec토토 카지노ds.